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  • The Human Ageing Genomic Resources (HAGR) is a collection of databases and tools for the biology and genetics of ageing. HAGR features several databases with high-quality, manually-curated data: 1) GenAge, a database of genes associated with ageing in humans and model organisms; 2) AnAge, an extensive collection of longevity records and complementary traits for over 4,000 vertebrate species; and 3) GenDR, a database containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction.

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  • This repository provides access to a wide range of work produced by members of Nottingham Trent University, including journal articles, authored and edited books, book chapters, conference contributions and digital and visual media. A full description of all items is provided and, whenever possible, the full text (or equivalent).

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  • The mission of BioStudies is to provide access to all the data outputs of a life sciences study from a single place, by organising links to data in other databases at EMBL-EBI or elsewhere, as well as hosting data and metadata that do not fit anywhere else. The database accepts submissions via an online tool, or in a simple tab-delimited format. BioStudies provides rich mechanisms for defining and using metadata guidelines specific for a particular data source such as a project or a community, and organises datasets in collections.

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  • Paramecia are unicellular eukaryotes of large size (~ 120 micrometers for P aurelia species) that belong to the ciliate phylum. Ciliates, like the Last Eukaryotic Common Ancestor, have the axonemal structure in the form of vibrating cilia that assure locomotion and food capture and are essential for pairing of paramecia of opposite mating types during conjugation (sexual reproduction). Like multicellular eukaryotes, ciliates separate germinal and somatic functions, harbouring two different kinds of nuclei. A diploid germinal micronucleus transmits the genetic information to the next sexual generation, while a polyploid somatic macronucleus is responsible for gene expression. Reproducible DNA elimination, which occurs in many animal lineages, takes place in ciliates during sexual reproduction, when a new somatic macronucleus develops from a copy of the germline micronucleus. The somatic genomes of numerous Paramecium species are being sequenced and annotated. ParameciumDB integrates the genomes as they become available, to provide resources for functional and comparative genomics to the community. ParameciumDB interfaces and tools have been redesigned. Your feedback is welcome.

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5,224 Data sources
  • The Human Ageing Genomic Resources (HAGR) is a collection of databases and tools for the biology and genetics of ageing. HAGR features several databases with high-quality, manually-curated data: 1) GenAge, a database of genes associated with ageing in humans and model organisms; 2) AnAge, an extensive collection of longevity records and complementary traits for over 4,000 vertebrate species; and 3) GenDR, a database containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction.

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  • This repository provides access to a wide range of work produced by members of Nottingham Trent University, including journal articles, authored and edited books, book chapters, conference contributions and digital and visual media. A full description of all items is provided and, whenever possible, the full text (or equivalent).

    more_vert
  • The mission of BioStudies is to provide access to all the data outputs of a life sciences study from a single place, by organising links to data in other databases at EMBL-EBI or elsewhere, as well as hosting data and metadata that do not fit anywhere else. The database accepts submissions via an online tool, or in a simple tab-delimited format. BioStudies provides rich mechanisms for defining and using metadata guidelines specific for a particular data source such as a project or a community, and organises datasets in collections.

    more_vert
  • Paramecia are unicellular eukaryotes of large size (~ 120 micrometers for P aurelia species) that belong to the ciliate phylum. Ciliates, like the Last Eukaryotic Common Ancestor, have the axonemal structure in the form of vibrating cilia that assure locomotion and food capture and are essential for pairing of paramecia of opposite mating types during conjugation (sexual reproduction). Like multicellular eukaryotes, ciliates separate germinal and somatic functions, harbouring two different kinds of nuclei. A diploid germinal micronucleus transmits the genetic information to the next sexual generation, while a polyploid somatic macronucleus is responsible for gene expression. Reproducible DNA elimination, which occurs in many animal lineages, takes place in ciliates during sexual reproduction, when a new somatic macronucleus develops from a copy of the germline micronucleus. The somatic genomes of numerous Paramecium species are being sequenced and annotated. ParameciumDB integrates the genomes as they become available, to provide resources for functional and comparative genomics to the community. ParameciumDB interfaces and tools have been redesigned. Your feedback is welcome.

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