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  • Paramecia are unicellular eukaryotes of large size (~ 120 micrometers for P aurelia species) that belong to the ciliate phylum. Ciliates, like the Last Eukaryotic Common Ancestor, have the axonemal structure in the form of vibrating cilia that assure locomotion and food capture and are essential for pairing of paramecia of opposite mating types during conjugation (sexual reproduction). Like multicellular eukaryotes, ciliates separate germinal and somatic functions, harbouring two different kinds of nuclei. A diploid germinal micronucleus transmits the genetic information to the next sexual generation, while a polyploid somatic macronucleus is responsible for gene expression. Reproducible DNA elimination, which occurs in many animal lineages, takes place in ciliates during sexual reproduction, when a new somatic macronucleus develops from a copy of the germline micronucleus. The somatic genomes of numerous Paramecium species are being sequenced and annotated. ParameciumDB integrates the genomes as they become available, to provide resources for functional and comparative genomics to the community. ParameciumDB interfaces and tools have been redesigned. Your feedback is welcome.

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  • PDX Finder is an open repository for the upload and storage of clinical, genomic and functional Patient-Derived Xenograph (PDX) data which provides a comprehensive global catalogue of PDX models available for researchers across distributed repository databases. Integrated views are provided for histopathological image data, molecular classification of tumors, host mouse strain metadata, tumor genomic data and metrics on tumor response to chemotherapeutics. The data model for PDX Finder is based on the minimal information standard for PDX models developed in collaboration with a broad range of stakeholders who create and/or use PDX models in basic and pre-clinical cancer research.

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  • This repository contains publications on the subjects of Philosophy, Psychology and Theology by the staff of Heythorpe College. Open access is only allowed to some full text items, most items have restricted access.

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  • This site is an institutional repository providing access to the research output of the institution. Many items are not available as full-text. Users may set up RSS and Atom feeds to be alerted to new content.

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  • MADIS is the open access institutional repository of Ifsttar laboratories and jointly Managed Research Units (UMRs) productions. It is managed by the Library staff of Ifsttar. The interface is in French.

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  • This is the official University of St Andrews institutional repository. Content is primarily electronic theses and research publications, with some grey literature, monographs and other material affiliated to the University. Full text content is provided for all research publications in the repository, and wherever possible (following embargoes) for electronic theses.

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6,146 Data sources
  • Paramecia are unicellular eukaryotes of large size (~ 120 micrometers for P aurelia species) that belong to the ciliate phylum. Ciliates, like the Last Eukaryotic Common Ancestor, have the axonemal structure in the form of vibrating cilia that assure locomotion and food capture and are essential for pairing of paramecia of opposite mating types during conjugation (sexual reproduction). Like multicellular eukaryotes, ciliates separate germinal and somatic functions, harbouring two different kinds of nuclei. A diploid germinal micronucleus transmits the genetic information to the next sexual generation, while a polyploid somatic macronucleus is responsible for gene expression. Reproducible DNA elimination, which occurs in many animal lineages, takes place in ciliates during sexual reproduction, when a new somatic macronucleus develops from a copy of the germline micronucleus. The somatic genomes of numerous Paramecium species are being sequenced and annotated. ParameciumDB integrates the genomes as they become available, to provide resources for functional and comparative genomics to the community. ParameciumDB interfaces and tools have been redesigned. Your feedback is welcome.

    more_vert
  • PDX Finder is an open repository for the upload and storage of clinical, genomic and functional Patient-Derived Xenograph (PDX) data which provides a comprehensive global catalogue of PDX models available for researchers across distributed repository databases. Integrated views are provided for histopathological image data, molecular classification of tumors, host mouse strain metadata, tumor genomic data and metrics on tumor response to chemotherapeutics. The data model for PDX Finder is based on the minimal information standard for PDX models developed in collaboration with a broad range of stakeholders who create and/or use PDX models in basic and pre-clinical cancer research.

    more_vert
  • This repository contains publications on the subjects of Philosophy, Psychology and Theology by the staff of Heythorpe College. Open access is only allowed to some full text items, most items have restricted access.

    more_vert
  • more_vert
  • This site is an institutional repository providing access to the research output of the institution. Many items are not available as full-text. Users may set up RSS and Atom feeds to be alerted to new content.

    more_vert
  • more_vert
  • more_vert
  • MADIS is the open access institutional repository of Ifsttar laboratories and jointly Managed Research Units (UMRs) productions. It is managed by the Library staff of Ifsttar. The interface is in French.

    more_vert
  • more_vert
  • This is the official University of St Andrews institutional repository. Content is primarily electronic theses and research publications, with some grey literature, monographs and other material affiliated to the University. Full text content is provided for all research publications in the repository, and wherever possible (following embargoes) for electronic theses.

    more_vert
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