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  • Drug Mechanism Database (DrugMechDB) compiles curated mechanism of action linking a drug to a disease. Most drug mechanisms are described simply as a protein target, or a pathway, that then treats the disease. However, there are usually more steps across a biological knowledge graph required to traverse from the target through its mechanism to the reduction of a disease. DrugMechDB catalog a subset of known drug-disease indications as a path through a network of biomedical entities.

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  • PiroplasmaDB is one of the databases that can be accessed through the VEuPathDB portal. While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the VEuPathDB portal offers an entry point to all these resources, and the opportunity to leverage orthology for searches across genera.

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  • The Common Fund’s Gabriella Miller Kids First Pediatric Research Program (Kids First) has developed the Kids First Data Resource, a large-scale data resource to help researchers uncover new insights into the biology of childhood cancer and structural birth defects. It provides clinically annotated genomic data and is integrated with several tools to accelerate pediatric disease research. The Kids First Data Resource Portal allows users to query, or search, Kids First datasets, build virtual cohorts, or collections, of individual participants, and identify datasets for analysis. CAVATICA, built by Seven Bridges Genomics, allows users to run bioinformatics workflows in a cloud-based environment.

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  • Surface Radiation Budget Network Database (SURFRAD) supports climate research with accurate, continuous, long-term measurements of the surface radiation budget over the United States. Data are downloaded, quality controlled, and processed into daily files that are distributed in near real time. Observations from SURFRAD have been used for evaluating satellite-based estimates of surface radiation, and for validating hydrologic, weather prediction, and climate models.

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5,986 Data sources
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  • Drug Mechanism Database (DrugMechDB) compiles curated mechanism of action linking a drug to a disease. Most drug mechanisms are described simply as a protein target, or a pathway, that then treats the disease. However, there are usually more steps across a biological knowledge graph required to traverse from the target through its mechanism to the reduction of a disease. DrugMechDB catalog a subset of known drug-disease indications as a path through a network of biomedical entities.

    more_vert
  • PiroplasmaDB is one of the databases that can be accessed through the VEuPathDB portal. While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the VEuPathDB portal offers an entry point to all these resources, and the opportunity to leverage orthology for searches across genera.

    more_vert
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  • The Common Fund’s Gabriella Miller Kids First Pediatric Research Program (Kids First) has developed the Kids First Data Resource, a large-scale data resource to help researchers uncover new insights into the biology of childhood cancer and structural birth defects. It provides clinically annotated genomic data and is integrated with several tools to accelerate pediatric disease research. The Kids First Data Resource Portal allows users to query, or search, Kids First datasets, build virtual cohorts, or collections, of individual participants, and identify datasets for analysis. CAVATICA, built by Seven Bridges Genomics, allows users to run bioinformatics workflows in a cloud-based environment.

    more_vert
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  • Surface Radiation Budget Network Database (SURFRAD) supports climate research with accurate, continuous, long-term measurements of the surface radiation budget over the United States. Data are downloaded, quality controlled, and processed into daily files that are distributed in near real time. Observations from SURFRAD have been used for evaluating satellite-based estimates of surface radiation, and for validating hydrologic, weather prediction, and climate models.

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